Skeletal Muscle Metastases from Squamous Cell Carcinoma of the Cervix: Report of Two Cases With Literature Review

Int J Gynecol Pathol. 2017 Jan;36(1):95-100. doi: 10.1097/PGP.0000000000000298.

Abstract

Cervical carcinoma is the second most common female malignancy worldwide. It usually spreads by direct local extension or the lymphatic vessels. Hematogenous dissemination with distant skeletal muscle metastases is a rare phenomenon. We report here 2 patients whose recurrent squamous cell carcinomas of the cervix presented with symptomatic skeletal muscle metastases affecting the muscles of the thoracic wall and forearm, respectively. We also discuss the differential diagnosis and comprehensively review the previously published literature on this rare presentation of cervical carcinoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / pathology*
  • Cervix Uteri / pathology
  • Diagnosis, Differential
  • Female
  • Humans
  • Muscle Neoplasms / diagnostic imaging
  • Muscle Neoplasms / pathology
  • Muscle Neoplasms / secondary*
  • Muscle, Skeletal / pathology
  • Neoplasm Recurrence, Local
  • Uterine Cervical Neoplasms / diagnostic imaging
  • Uterine Cervical Neoplasms / pathology*