CDK4/6 inhibition: the late harvest cycle begins

Oncotarget. 2016 Aug 2;7(31):48854-48856. doi: 10.18632/oncotarget.9576.

Authors

Shom Goel¹, Jean J Zhao^{2

3

4}

Affiliations

¹ Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
² Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
³ Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
⁴ The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

No abstract available

Keywords: CDK4/6; abemaciclib; cancer; cell cycle; cyclin.

Publication types

Editorial

MeSH terms

Animals
Cell Cycle / drug effects*
Cyclin-Dependent Kinase 4 / antagonists & inhibitors*
Cyclin-Dependent Kinase 6 / antagonists & inhibitors*
Humans
Mice
Neoplasms / drug therapy*
Neoplasms / enzymology*

Substances

CDK4 protein, human
CDK6 protein, human
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinase 6