Zika virus infection and once again the risk from other neglected diseases

Trop Doct. 2016 Jul;46(3):159-65. doi: 10.1177/0049475516656101.

Abstract

Since the first cases of Zika were identified and reported in Brazil, the magnitude and consequences of the outbreak in the Americas have increased tremendously, leading the World Health Organization to consider Zika and its link with clusters of microcephaly a Public Health Emergency of International Concern. Only a previous large outbreak in French Polynesia was known and no neurological anomalies have been reported. Differences in African and Asian lineage and differences in genetic evolution of the Zika virus may possibly provide an explanation for the development of the recent outbreaks and their variable presentation. However, the similar clinical presentation between Zika and other diseases like Dengue and Chikungunya can support that Zika has been circulating and spreading inadvertently. This hypothesis gains strength when rates of laboratory confirmation diagnosis for Dengue are observed in Brazil and Colombia, two of the most affected countries by Zika virus (ZIKV) infection.The lack of attention and resources on neglected diseases supposes a huge risk that new lethal pathogens camouflage themselves to spread into large areas and populations.

Keywords: Zika; dengue; epidemiological surveillance; neglected diseases; uutbreaks.

MeSH terms

  • Brazil / epidemiology
  • Chikungunya Fever / epidemiology
  • Communicable Diseases, Emerging / epidemiology*
  • Communicable Diseases, Emerging / virology
  • Dengue / epidemiology
  • Disease Outbreaks*
  • Epidemiological Monitoring
  • Humans
  • Microcephaly / epidemiology*
  • Neglected Diseases*
  • World Health Organization
  • Zika Virus / isolation & purification
  • Zika Virus Infection / diagnosis
  • Zika Virus Infection / epidemiology*
  • Zika Virus Infection / transmission
  • Zika Virus Infection / virology