[Future applications of mass spectrometry in microbiology]

Abstract

MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry (MS) has been vigorously introduced in many clinical microbiology laboratories for the rapid and accurate identification of bacteria and fungi. In fact, the implementation of this methodology can be considered a revolution in these laboratories. In addition to microbial identification, MALDI-TOF MS is being used for the detection of some mechanisms of antibiotic resistance and for the molecular typing of bacteria. A number of current and future applications that increase the versatility of this methodology may also be mentioned. Among these are its direct application on clinical samples, the detection of toxins or specific microbial antigens, and its application in the fields of virology and parasitology.

Keywords: Antigens; Antígenos; Clinical samples; Espectrometría de masas; MALDI-TOF; Mass spectrometry; Muestras clínicas; Parasitology; Parasitología; Toxins; Toxínas; Virology; Virología.