Minimum 5-year follow-up outcomes for single-stage transpedicular debridement, posterior instrumentation and fusion in the management of thoracic and thoracolumbar spinal tuberculosis in adults

Br J Neurosurg. 2016 Dec;30(6):666-671. doi: 10.1080/02688697.2016.1206182. Epub 2016 Jul 8.

Abstract

Aim: The aim of this retrospective clinical study is to evaluate the long-term outcomes for single-stage transpedicular debridement, posterior instrumentation and fusion in the management of thoracic and thoracolumbar spinal tuberculosis in adults.

Methods: Fifty-nine adult patients with thoracic and thoracolumbar spinal tuberculosis underwent single-stage transpedicular debridement, posterior instrumentation and fusion. These patients were followed for a minimum of 5 years. Patients were assigned to one of two groups according to the infected anatomic segment. In the thoracic spinal tuberculosis group, there were 28 cases (17 males, 11 females) with a mean age of 38.9 years; in the thoracolumbar spinal tuberculosis group, there were 31 cases (19 males, 12 females) with a mean age of 40.3 years. All cases were evaluated clinically using the visual analog scale (VAS), Kirkaldy-Willis criteria and the American Spinal Injury Association (ASIA) impairment scale. Radiographs were performed for measuring the angle of kyphosis and scoliosis. Complications related to surgery were recorded.

Results: All patients successfully resolved their infections, experienced one or more ASIA grades of improvement, and improved in their VAS pain scores at final follow-up. In both groups, patient-reported outcomes reached over 90% excellent or good results using Kirkaldy-Willis criteria. The loss of kyphotic angle correction was 2.6° in the thoracic spinal tuberculosis group and 3.2° in the thoracolumbar spinal tuberculosis group. No scoliosis was observed in either group. Fifty-eight (98.3%) cases achieved solid bony fusion. In the thoracolumbar spinal tuberculosis group, one patient experienced screw loosening, and another patient with nonunion and rod breakage underwent revision surgery.

Conclusions: The technique of single-stage transpedicular debridement, posterior instrumentation and fusion is an effective method for the treatment of thoracic and thoracolumbar spinal tuberculosis in adults. Long-term postoperative clinical and radiological outcomes were satisfactory.

Keywords: Pott’s disease; interbody grafting; posterior midline approach; posterior spinal instrumentation; thoracic spine.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antitubercular Agents / therapeutic use
  • Bone Screws
  • Debridement / methods*
  • Female
  • Humans
  • Internal Fixators*
  • Kyphosis / diagnostic imaging
  • Kyphosis / etiology
  • Lumbar Vertebrae
  • Male
  • Middle Aged
  • Pain Measurement
  • Postoperative Care
  • Reoperation
  • Retrospective Studies
  • Scoliosis / diagnostic imaging
  • Scoliosis / etiology
  • Spinal Fusion / methods*
  • Thoracic Vertebrae
  • Treatment Outcome
  • Tuberculosis, Spinal / diagnostic imaging
  • Tuberculosis, Spinal / surgery*

Substances

  • Antitubercular Agents