Serological evidence of hantavirus infection in an urban area in Mato Grosso State, Brazil

Rev Soc Bras Med Trop. 2016 May-Jun;49(3):348-50. doi: 10.1590/0037-8682-0026-2016.

Abstract

Introduction: In Brazil, Mato Grosso (MT) has the highest number of hantavirus cardiopulmonary syndrome cases. Our study aimed to identify anti-hantavirus antibodies in the sera of patients from Sinop, MT, presenting with acute febrile illness.

Methods: A retrospective analysis of data for 198 sera samples assessed using enzyme-linked immunosorbent assay (ELISA) was conducted.

Results: Immunoglobulins G (IgGs) against the hantavirus nucleoprotein were found in 13.6% of the tested sera. No sample had immunoglobulin M (IgM) antibodies to hantavirus. Seropositivity occurred mainly in female residents in urban areas who worked around the household.

Conclusions: Our findings suggest circulation of hantavirus in Sinop.

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Antibodies, Viral / blood*
  • Brazil / epidemiology
  • Child
  • Child, Preschool
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Hantavirus Infections / diagnosis*
  • Hantavirus Infections / epidemiology
  • Humans
  • Immunoglobulin G / blood*
  • Immunoglobulin M / blood*
  • Male
  • Middle Aged
  • Orthohantavirus / immunology*
  • Risk Factors
  • Rural Population
  • Seroepidemiologic Studies
  • Urban Population
  • Young Adult

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Immunoglobulin M