Electrophysiological mechanisms of biased response to smoking-related cues in young smokers

Jiadong Cheng; Yanyan Guan; Yajuan Zhang; Yanzhi Bi; Limei Bu; Yangding Li; Sha Shi; Peng Liu; Xiaoqi Lu; Dahua Yu; Kai Yuan

doi:10.1016/j.neulet.2016.06.062

Electrophysiological mechanisms of biased response to smoking-related cues in young smokers

Neurosci Lett. 2016 Aug 26:629:85-91. doi: 10.1016/j.neulet.2016.06.062. Epub 2016 Jun 29.

Authors

Jiadong Cheng¹, Yanyan Guan¹, Yajuan Zhang¹, Yanzhi Bi¹, Limei Bu², Yangding Li¹, Sha Shi¹, Peng Liu¹, Xiaoqi Lu², Dahua Yu³, Kai Yuan⁴

Affiliations

¹ School of Life Science and Technology, Xidian University, Xi'an, People's Republic of China; Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, People's Republic of China.
² Information Processing Laboratory, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia, People's Republic of China.
³ Information Processing Laboratory, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia, People's Republic of China. Electronic address: fmydh@imust.edu.cn.
⁴ School of Life Science and Technology, Xidian University, Xi'an, People's Republic of China; Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, People's Republic of China; Information Processing Laboratory, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia, People's Republic of China. Electronic address: kyuan@xidian.edu.cn.

PMID: 27373532
DOI: 10.1016/j.neulet.2016.06.062

Abstract

Cigarette smoking during young adult may result in serious health issues in later life. Hence, it is extremely necessary to study the smoking neurophysiological mechanisms in this critical transitional period. However, few studies revealed the electrophysiological mechanisms of cognitive processing biases in young adult smokers. In present study, nineteen young smokers with 12h abstinent and 19 matched nonsmokers were recruited. By employing event-related potentials (ERP) measurements during a smoking cue induced craving task, electrophysiological brain responses were compared between the young adult smokers and nonsmokers. The Slow Positive Wave (SPW) amplitude of smoking-related cues was enhanced in young adult smokers compared with nonsmokers. In addition, increased P300/SPW component of smoking-related cues relative to neutral cues were found in young adult smokers. Meanwhile, a positive correlation between Cigarette Per Day (CPD) and the amplitude of ERPs wave (P300/SPW) at anterior (Fz), central (Cz) were observed in young adult smokers. Our findings provided direct electrophysiological evidence for the cognitive processing bias of smoking cue and may shed new insights into the smoking behavior in young adult smokers.

Keywords: Cognitive processing bias; Event-related potentials (ERP); P300; Slow Positive Wave (SPW); Young adult smokers.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Cerebral Cortex / physiopathology*
Cognition / physiology*
Craving / physiology*
Cues*
Electroencephalography
Event-Related Potentials, P300
Humans
Male
Smoking / physiopathology*
Smoking / psychology*
Young Adult