Steroid 5-reductases are functional during early frog development and are regulated via DNA methylation

Mech Dev. 2016 Aug:141:14-24. doi: 10.1016/j.mod.2016.06.005. Epub 2016 Jul 1.

Authors

Sonja Bissegger¹, Valerie S Langlois²

Affiliations

¹ Chemistry and Chemical Engineering Department, Royal Military College of Canada, Kingston, ON, Canada. Electronic address: sonja.bissegger@rmc.ca.
² Chemistry and Chemical Engineering Department, Royal Military College of Canada, Kingston, ON, Canada. Electronic address: valerie.langlois@rmc.ca.

PMID: 27373510
DOI: 10.1016/j.mod.2016.06.005

No abstract available

Keywords: DNA methylation; Silurana tropicalis; in situ hybridization; srd5α1; srd5α2; srd5α3.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

3-Oxo-5-alpha-Steroid 4-Dehydrogenase / metabolism*
Animals
DNA Methylation*
Female
Gene Expression Regulation, Developmental
Humans
In Situ Hybridization
Male
Promoter Regions, Genetic / genetics
RNA, Messenger / genetics
RNA, Messenger / metabolism
Xenopus / embryology*
Xenopus / metabolism*
Xenopus Proteins / genetics
Xenopus Proteins / metabolism

Substances

RNA, Messenger
Xenopus Proteins
3-Oxo-5-alpha-Steroid 4-Dehydrogenase
steroid-5alpha-reductase type 1