Equine-like G3 rotavirus in Hungary, 2015 - Is it a novel intergenogroup reassortant pandemic strain?

Acta Microbiol Immunol Hung. 2016 Jun;63(2):243-55. doi: 10.1556/030.63.2016.2.8.

Abstract

Novel, intergenogroup reassortant G3 rotavirus strains are spreading in at least three continents: Asia, Australia, and Europe. The present study provides evidence that a closely related G3P[8] strain circulated in Hungary during 2015. Whole genome sequencing and phylogenetic analysis showed that the identified strain continues to evolve by reassortment. This observation demonstrates the genomic plasticity of the novel strain, which is thought to be a prerequisite of the success of emerging rotavirus genotypes.

Keywords: next generation sequencing; phylogenetic analysis; surveillance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Asia / epidemiology
  • Australia / epidemiology
  • Europe
  • Genotype
  • Horse Diseases / epidemiology
  • Horse Diseases / virology*
  • Horses
  • Humans
  • Hungary / epidemiology
  • Pandemics
  • Phylogeny
  • Reassortant Viruses / classification
  • Reassortant Viruses / genetics
  • Reassortant Viruses / isolation & purification*
  • Rotavirus / classification
  • Rotavirus / genetics
  • Rotavirus / isolation & purification*
  • Rotavirus Infections / epidemiology
  • Rotavirus Infections / veterinary*
  • Rotavirus Infections / virology*