Montreal Cognitive Assessment and Mini-Mental State Examination reliable change indices in healthy older adults

Int J Geriatr Psychiatry. 2017 Aug;32(8):868-875. doi: 10.1002/gps.4539. Epub 2016 Jun 29.

Abstract

Objective: Cognitive tests are used repeatedly to assess the treatment response or progression of cognitive disorders. The Montreal Cognitive Assessment (MoCA) is a valid screening test for mild cognitive impairment. The aim of our study was to establish 90% reliable change indices (RCI) for the MoCA together with the Mini-Mental State Examination (MMSE) in cognitively healthy older adults.

Method: We analyzed 197 cognitively healthy and functional independent volunteers aged 60-94 years, who met strict inclusion criteria for four consecutive years. The RCI methods by Chelune and Hsu were used.

Results: For 1, 2, and 3 years, the 90% RCI for MoCA using Chelune's formula were -4 ≤, ≥4; -4 ≤, ≥4 and -5 ≤, ≥4 points, respectively, and -3 ≤, ≥3 for the MMSE each year. Ninety percent RCI for MoCA using Hsu's formula ranged from -6 to 0, respectively, and +3 to +8 dependent on the baseline MoCA.

Conclusion: Our study demonstrated RCI for the MoCA and MMSE in a 3-year time period that can be used for the estimation of cognitive decline or improvement in clinical settings. Copyright © 2016 John Wiley & Sons, Ltd.

Keywords: aging; cognition; reliability and validity.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Analysis of Variance
  • Brief Psychiatric Rating Scale
  • Cognitive Dysfunction / diagnosis*
  • Disease Progression
  • Female
  • Geriatric Assessment / methods
  • Humans
  • Male
  • Mental Status and Dementia Tests*
  • Middle Aged
  • Neuropsychological Tests*