Expansion of the E138A mutation in newly diagnosed HIV-infected patients in Gran Canaria

Diagn Microbiol Infect Dis. 2016 Sep;86(1):58-60. doi: 10.1016/j.diagmicrobio.2016.06.014. Epub 2016 Jun 17.

Abstract

Molecular epidemiology allows us to know local HIV transmission and to design strategies of prevention. We studied 25 HIV newly diagnosed patients with the E138A mutation since the year 2010. Most transmission networks involved young and promiscuous men who have sex with men. Recent infection was only documented in patients grouped into the smaller clusters.

Keywords: HIV/AIDS; Phylogenetic analysis; Prevention strategies; Rilpivirine; Transmission networks.

MeSH terms

  • Adolescent
  • Adult
  • Cluster Analysis
  • Female
  • HIV / classification*
  • HIV / enzymology
  • HIV / genetics*
  • HIV / isolation & purification
  • HIV Infections / epidemiology*
  • HIV Infections / transmission
  • HIV Infections / virology*
  • HIV Reverse Transcriptase / genetics*
  • Humans
  • Male
  • Middle Aged
  • Molecular Epidemiology
  • Mutation, Missense*
  • Spain / epidemiology
  • Young Adult

Substances

  • HIV Reverse Transcriptase