Oral lichen planus: a literature review and update

Arch Dermatol Res. 2016 Oct;308(8):539-51. doi: 10.1007/s00403-016-1667-2. Epub 2016 Jun 27.

Abstract

Lichen planus (LP) is a common chronic inflammatory condition that can affect skin and mucous membranes, including the oral mucosa. Because of the anatomic, physiologic and functional peculiarities of the oral cavity, the oral variant of LP (OLP) requires specific evaluations in terms of diagnosis and management. In this comprehensive review, we discuss the current developments in the understanding of the etiopathogenesis, clinical-pathologic presentation, and treatment of OLP, and provide follow-up recommendations informed by recent data on the malignant potential of the disease as well as health economics evaluations.

Keywords: Oral lichen planus; Oral lichenoid lesions; Oral lichenoid reactions.

Publication types

  • Review

MeSH terms

  • Carcinogenesis
  • Drug-Related Side Effects and Adverse Reactions / complications
  • Graft vs Host Disease / complications
  • Humans
  • Lichen Planus, Oral / diagnosis*
  • Lichen Planus, Oral / etiology
  • Lichen Planus, Oral / pathology
  • Mouth / pathology*
  • Mouth Mucosa / pathology*
  • Skin / pathology*