Laparoscopic Davydov Procedure for the Creation of a Neovagina in Patients with Mayer-Rokitansky-Kuster-Hauser Syndrome: Analysis of 7 Cases

Tokai J Exp Clin Med. 2016 Jun 20;41(2):81-7.

Abstract

Objective: Several surgical techniques have been described for creating a neovagina in patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, however as yet there is no standardized treatment. The aim of this report is to assess anatomic and functional outcomes after the laparoscopic Davydov procedure for the creation of a neovagina in patients with MRKH syndrome.

Methods: Seven patients with MRKH syndrome underwent the laparoscopic Davydov technique from January 2005 to August 2010. The anatomic and functional results were evaluated after 3, 6, 12, 24, 36, 48, and 60 months.

Results: The surgical procedure was performed with no major complications except in one case in which an intraoperative bladder injury occurred and was successfully corrected. The mean duration of surgery was 162.9 minutes (range, 120-230 min). Mean lengths/widths (cm) of the neovagina were 6.4/2.6, 6.5/2.5, 6.5/2.8, 6.4/2.8, 7.1/2.8, and 7.2/2.8 at 3, 6,12, 24, 36, 48, and 60 postoperative months, respectively.

Conclusion: The laparoscopic Davydov procedure seems to be a safe and effective surgical treatment for patients with MRKH syndrome if postoperative intermittent self dilation was done.

MeSH terms

  • 46, XX Disorders of Sex Development / physiopathology
  • 46, XX Disorders of Sex Development / surgery*
  • Adolescent
  • Adult
  • Congenital Abnormalities / physiopathology
  • Congenital Abnormalities / surgery*
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Gynecologic Surgical Procedures / methods*
  • Humans
  • Laparoscopy / methods*
  • Mullerian Ducts / abnormalities*
  • Mullerian Ducts / physiopathology
  • Mullerian Ducts / surgery
  • Plastic Surgery Procedures / methods*
  • Time Factors
  • Treatment Outcome
  • Vagina / abnormalities*
  • Vagina / physiopathology
  • Vagina / surgery*
  • Young Adult

Supplementary concepts

  • Mullerian aplasia