Genome sequence of Prevotella intermedia SUNY aB G8-9K-3, a biofilm forming strain with drug-resistance

Braz J Microbiol. 2017 Jan-Mar;48(1):5-6. doi: 10.1016/j.bjm.2016.04.030. Epub 2016 Jun 9.

Abstract

Prevotella intermedia has long been known to be as the principal etiologic agent of periodontal diseases and associated with various systemic diseases. Previous studies showed that the intra-species difference exists in capacity of biofilm formation, antibiotic resistance, and serological reaction among P. intermedia strains. Here we report the genome sequence of P. intermedia SUNY aB G8-9K-3 (designated ATCC49046) that displays a relatively high antimicrobial resistant and biofilm-forming capacity. Genome sequencing information provides important clues in understanding the genetic bases of phenotypic differences among P. intermedia strains.

Keywords: Antimicrobial resistant; Biofilm-forming capacity; Prevotella intermedia.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Biofilms*
  • Computational Biology / methods
  • Drug Resistance, Bacterial*
  • Genome, Bacterial*
  • Genomics / methods
  • High-Throughput Nucleotide Sequencing*
  • Molecular Sequence Annotation
  • Polymorphism, Single Nucleotide
  • Prevotella intermedia / drug effects*
  • Prevotella intermedia / physiology*
  • Sequence Analysis, DNA

Substances

  • Anti-Bacterial Agents