Ag-CNT Architectures for Attomolar Dopamine Detection and 100-Fold Fluorescence Enhancements with Cellphone-Based Surface Plasmon-Coupled Emission Platform

Pradeep Kumar Badiya; Venkatesh Srinivasan; Tejkiran Pindi Jayakumar; Sai Sathish Ramamurthy

doi:10.1002/cphc.201600571

Ag-CNT Architectures for Attomolar Dopamine Detection and 100-Fold Fluorescence Enhancements with Cellphone-Based Surface Plasmon-Coupled Emission Platform

Chemphyschem. 2016 Sep 19;17(18):2791-4. doi: 10.1002/cphc.201600571. Epub 2016 Jul 6.

Authors

Pradeep Kumar Badiya¹, Venkatesh Srinivasan¹, Tejkiran Pindi Jayakumar¹, Sai Sathish Ramamurthy²

Affiliations

¹ Plasmonics Laboratory, Department of Chemistry, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, 515134, India.
² Plasmonics Laboratory, Department of Chemistry, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, 515134, India. rsaisathish@sssihl.edu.in.

PMID: 27338187
DOI: 10.1002/cphc.201600571

Abstract

We report cellphone-based detection of dopamine with attomolar sensitivity in clinical samples with the use of a surface plasmon-coupled emission (SPCE) platform. To this end, silver-coated carbon nanotubes were used as spacer and cavity materials on SPCE substrates to obtain up to 100-fold fluorescence enhancements. The presence of silver on the carbon nanotubes helped to overcome fluorescence quenching arising due to π-π interactions between the carbon nanotube and rhodamine 6G. The competing adsorption of dopamine versus rhodamine 6G on graphene oxide was utilized to develop this sensing platform.

Keywords: biosensors; carbon; dopamine; graphene; nanotubes.

MeSH terms

Cell Phone*
Fluorescence*
Metal Nanoparticles / chemistry
Nanotubes, Carbon / chemistry*
Particle Size
Silver / chemistry*
Surface Plasmon Resonance*
Surface Properties

Substances

Nanotubes, Carbon
Silver