Data on HLA class I/II profile in Brazilian pemphigus patients

Maria José Franco Brochado; Daniela Francisca Nascimento; Neifi Hassan Saloum Deghaide; Eduardo Antonio Donadi; Ana Maria Roselino

doi:10.1016/j.dib.2016.05.077

Data on HLA class I/II profile in Brazilian pemphigus patients

Data Brief. 2016 Jun 3:8:364-74. doi: 10.1016/j.dib.2016.05.077. eCollection 2016 Sep.

Authors

Maria José Franco Brochado¹, Daniela Francisca Nascimento¹, Neifi Hassan Saloum Deghaide², Eduardo Antonio Donadi², Ana Maria Roselino¹

Affiliations

¹ Division of Dermatology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
² Division of Clinical Immunology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

Abstract

Pemphigus are blistering autoimmune diseases related with genetic and environmental factors. Here we describe HLA genotyping in pemphigus patients. First, we review the HLA class I/II data on pemphigus reported in Brazilian samples and then present the HLA class I (-A, -B, -C) and class II (-DRB1, -DQA1, -DQB1) alleles related to susceptibility/resistance to pemphigus by comparing 86 patients with pemphigus foliaceus, 83 patients with pemphigus vulgaris, and 1592 controls from the northeastern region of the state of São Paulo, Southeastern Brazil. The data presented here are related to the manuscript "Differential HLA class I and class II associations in Pemphigus Foliaceus and Pemphigus Vulgaris patients from a prevalent Southeastern Brazilian region" Brochado et al. (2016) [1].