Light-independent pro-inflammatory and pro-oxidant effects of purified human hair melanins on keratinocyte cell cultures

Exp Dermatol. 2017 Jul;26(7):592-594. doi: 10.1111/exd.13122. Epub 2017 Jan 9.

Authors

Serena Lembo¹, Roberta Di Caprio¹, Raffaella Micillo¹, Anna Balato¹, Giuseppe Monfrecola¹, Lucia Panzella², Alessandra Napolitano²

Affiliations

¹ Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.
² Department of Chemical Sciences, University of Naples "Federico II", Naples, Italy.

PMID: 27306784
DOI: 10.1111/exd.13122

No abstract available

Keywords: inflammation; melanin; melanomagenesis; oxidation; pheomelanin.

Publication types

Letter

MeSH terms

Antioxidants
Apoptosis
Cell Line, Tumor
Cell Proliferation
Cells, Cultured
DNA Damage
Hair / metabolism*
Hair Color
Humans
Inflammation / immunology*
Keratinocytes / cytology
Keratinocytes / metabolism*
Light*
Lipid Peroxidation
Lipids / chemistry
Melanins / chemistry*
Melanins / metabolism
Mutation
Oxidants / chemistry*
Oxidation-Reduction
Reactive Oxygen Species / metabolism
Sunburn
Ultraviolet Rays

Substances

Antioxidants
Lipids
Melanins
Oxidants
Reactive Oxygen Species
pheomelanin