Assessing the perceived quality of brachial artery Flow Mediated Dilation studies for inclusion in meta-analyses and systematic reviews: Description of data employed in the development of a scoring ;tool based on currently accepted guidelines

Arno Greyling; Anke C C M van Mil; Peter L Zock; Daniel J Green; Lorenzo Ghiadoni; Dick H Thijssen; TIFN International Working Group on Flow Mediated Dilation

doi:10.1016/j.dib.2016.05.011

Assessing the perceived quality of brachial artery Flow Mediated Dilation studies for inclusion in meta-analyses and systematic reviews: Description of data employed in the development of a scoring ;tool based on currently accepted guidelines

Data Brief. 2016 May 13:8:73-7. doi: 10.1016/j.dib.2016.05.011. eCollection 2016 Sep.

Authors

Arno Greyling¹, Anke C C M van Mil², Peter L Zock³, Daniel J Green⁴, Lorenzo Ghiadoni⁵, Dick H Thijssen⁶; TIFN International Working Group on Flow Mediated Dilation

Affiliations

¹ Department of Physiology, Radboud University Medical Centre, Nijmegen, The Netherlands; Unilever R&D Vlaardingen, Vlaardingen, The Netherlands.
² Department of Physiology, Radboud University Medical Centre, Nijmegen, The Netherlands; TI Food and Nutrition, Wageningen, The Netherlands; Maastricht University Medical Centre, Maastricht, The Netherlands.
³ Unilever R&D Vlaardingen, Vlaardingen, The Netherlands; TI Food and Nutrition, Wageningen, The Netherlands.
⁴ School of Sports Science, Exercise and Health, The University of Western Australia, Crawley, Australia.
⁵ University of Pisa, Pisa, Italy.
⁶ Department of Physiology, Radboud University Medical Centre, Nijmegen, The Netherlands; Research institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.

Abstract

Brachial artery Flow Mediated Dilation (FMD) is widely used as a non-invasive measure of endothelial function. Adherence to expert consensus guidelines on FMD measurement has been found to be of vital importance to obtain reproducible data. This article lists the literature data which was considered in the development of a tool to aid in the objective judgement of the extent to which published studies adhered to expert guidelines for FMD measurement. Application of this tool in a systematic review of FMD studies (http://dx.doi.org/10.1016/j.atherosclerosis.2016.03.011) (Greyling et al., 2016 [1]) indicated that adherence to expert consensus guidelines is strongly correlated to the reproducibility of FMD data.

Keywords: Atherosclerosis; Cardiovascular disease; Endothelial function; Methodology; Reproducibility.