GHap: an R package for genome-wide haplotyping

Bioinformatics. 2016 Sep 15;32(18):2861-2. doi: 10.1093/bioinformatics/btw356. Epub 2016 Jun 9.

Abstract

The GHap R package was designed to call haplotypes from phased marker data. Given user-defined haplotype blocks (HapBlock), the package identifies the different haplotype alleles (HapAllele) present in the data and scores sample haplotype allele genotypes (HapGenotype) based on HapAllele dose (i.e. 0, 1 or 2 copies). The output is not only useful for analyses that can handle multi-allelic markers, but is also conveniently formatted for existing pipelines intended for bi-allelic markers.

Availability and implementation: https://cran.r-project.org/package=GHap

Contact: ytutsunomiya@gmail.com

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • Computational Biology / methods
  • Computer Simulation
  • Electronic Data Processing
  • Genotype
  • Haplotypes*
  • Humans
  • Linear Models
  • Software*