Smart Implants as a Novel Strategy to Regenerate Well-Founded Cartilage

Trends Biotechnol. 2017 Jan;35(1):8-11. doi: 10.1016/j.tibtech.2016.05.008. Epub 2016 Jun 6.

Abstract

Here we explore a new generation of smart, living implants, combining not only active therapeutics but also stem cells, as a novel strategy to regenerate stabilised cartilage and avoid prostheses. This process can regenerate the subchondral bone foundation, which is currently difficult in the clinic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cartilage / cytology*
  • Cartilage / growth & development*
  • Chondrocytes / cytology*
  • Chondrocytes / transplantation*
  • Equipment Design
  • Guided Tissue Regeneration / instrumentation*
  • Guided Tissue Regeneration / methods
  • Humans
  • Regeneration / physiology*
  • Tissue Engineering / instrumentation
  • Tissue Engineering / methods
  • Tissue Scaffolds*