A new phenolic glycoside from Saprosma merrillii

Nat Prod Res. 2016 Nov;30(21):2429-33. doi: 10.1080/14786419.2016.1195382. Epub 2016 Jun 9.

Abstract

A new phenolic glycoside derivative, saproglucoside (1), along with five known phenolic glycoside derivatives (2-6) were isolated from the stems of Saprosma merrillii. The structure of the new compound 1 was determined by 1D and 2D NMR as well as by HRESIMS and hydrolysis. The inhibitory activities of all compounds against seven pathogenic bacteria and two cancer cell lines were evaluated.

Keywords: Antibacterial activity; Saprosma merrillii; phenolic glycoside derivatives.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Cell Line, Tumor
  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • Glucosides / pharmacology
  • Humans
  • Magnetic Resonance Spectroscopy
  • Phenols / chemistry
  • Phenols / isolation & purification*
  • Phenols / pharmacology
  • Rubiaceae / chemistry*

Substances

  • Anti-Bacterial Agents
  • Antineoplastic Agents, Phytogenic
  • Glucosides
  • Phenols
  • saproglucoside