[Treatment of cryptococcal meningitis by use of shunting and review in literature]

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016 May;41(5):541-7. doi: 10.11817/j.issn.1672-7347.2016.05.015.
[Article in Chinese]

Abstract

Objective: To evaluate the time and effect of shunt operation on cryptococcal meningitis.

Methods: A total 7 patients received shunt operation for the therapy of cryptococcal meningitis patients and the data was retrospectively analyzed.

Results: Intracranial hypertension-caused symptoms were resolved immediately. There was no complication, no infection dissemination and no recrudescence of cryptococcal meningitis.

Conclusion: Shunt operation is effective for intracranial hypertension caused by cryptococcal meningitis. It does not affect the antifungal treatment.

目的:探讨分流手术在新型隐球菌脑膜炎患者治疗中的时机并评价其疗效。方法:回顾性分析7例采取分流手术治疗新型隐球菌脑膜炎患者的经过。结果:7例患者颅内压得到了有效的控制,相关症状明显缓解。住院及随访期间未出现与分流手术相关的并发症,未发生因分流手术造成的隐球菌播散及难治性隐球菌感染,也未发生因此导致的感染复燃。结论:分流手术可以有效缓解新型隐球菌脑膜炎所致的颅内压增高,且不对抗隐球菌的治疗产生不良影响。.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antifungal Agents / therapeutic use
  • Drainage*
  • Humans
  • Intracranial Hypertension / surgery*
  • Meningitis, Cryptococcal / drug therapy
  • Meningitis, Cryptococcal / surgery*
  • Recurrence
  • Retrospective Studies

Substances

  • Antifungal Agents