Histologic Evidence for Arteriovenous Malformation-Like Vasculature Occurring within an Intracerebral Schwannoma: A Case Report and Review of the Literature

World Neurosurg. 2016 Aug:92:582.e9-582.e13. doi: 10.1016/j.wneu.2016.05.078. Epub 2016 Jun 3.

Abstract

Background: The phenomenon of intracerebral schwannoma is exceedingly rare, and its etiology still a matter of debate. No documented cases of intracerebral schwannoma containing vascular elements consistent with those of an arteriovenous malformation (AVM) have been reported. We describe such a case here.

Case description: A left temporal intraparenchymal lesion was discovered incidentally in a 34-year-old man after he suffered a mild trauma. The lesion was resected and found on histologic examination to be an intracerebral schwannoma with AVM-like vasculature. The patient made a full recovery after resection.

Conclusions: To our knowledge, this is the first case of an intracerebral schwannoma with AVM-like characteristics to be reported in the literature. We hypothesize that the co-occurrence of this rare pathologic entity is caused by an interrelated etiologic process, with the tumor microenvironment of the schwannoma inciting the development of the vascular malformation.

Keywords: Arteriovenous malformation; Intracerebral; Intraparenchymal schwannoma; Schwannoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Brain Edema / diagnostic imaging
  • Brain Edema / etiology
  • Brain Neoplasms / complications*
  • Brain Neoplasms / diagnostic imaging
  • Cerebral Angiography
  • Humans
  • Intracranial Arteriovenous Malformations / complications*
  • Intracranial Arteriovenous Malformations / diagnostic imaging
  • Intracranial Arteriovenous Malformations / surgery*
  • Male
  • Neurilemmoma / complications*
  • Neurilemmoma / diagnostic imaging
  • S100 Proteins / metabolism
  • Temporal Lobe / pathology
  • Temporal Lobe / surgery
  • Tomography Scanners, X-Ray Computed

Substances

  • S100 Proteins