Oral Metformin Ameliorates Bleomycin-Induced Skin Fibrosis

J Invest Dermatol. 2016 Sep;136(9):1892-1894. doi: 10.1016/j.jid.2016.05.097. Epub 2016 May 29.

Affiliations

¹ Department of Health Sciences, University of Catanzaro "Magna Graecia," Catanzaro, Italy. Electronic address: francesco.ursini@yahoo.it.
² Department of Health Sciences, University of Catanzaro "Magna Graecia," Catanzaro, Italy.
³ Department of Pathology, Regina Elena National Cancer Institute, Rome, Italy.
⁴ Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy.

PMID: 27251791
DOI: 10.1016/j.jid.2016.05.097

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Administration, Oral
Animals
Bleomycin / toxicity
Disease Models, Animal
Female
Fibrosis
Humans
Metformin / therapeutic use*
Mice
Mice, Inbred C3H
Scleroderma, Systemic / chemically induced
Scleroderma, Systemic / drug therapy*
Scleroderma, Systemic / pathology
Skin / drug effects
Skin / pathology*

Substances

Bleomycin
Metformin