T2-Filtered T2 - T2 Exchange NMR

Marcel Nogueira d'Eurydice; Elton Tadeu Montrazi; Carlos Alberto Fortulan; Tito José Bonagamba

doi:10.1063/1.4951712

T2-Filtered T2 - T2 Exchange NMR

J Chem Phys. 2016 May 28;144(20):204201. doi: 10.1063/1.4951712.

Authors

Marcel Nogueira d'Eurydice¹, Elton Tadeu Montrazi¹, Carlos Alberto Fortulan², Tito José Bonagamba¹

Affiliations

¹ Instituto de Física de São Carlos, Universidade de São Paulo, CP 369, 13560-970 São Carlos, São Paulo, Brazil.
² Escola de Engenharia de São Carlos, Universidade de São Paulo, CP 359, 13560-970 São Carlos, São Paulo, Brazil.

PMID: 27250299
DOI: 10.1063/1.4951712

Abstract

This work introduces an alternative way to perform the T2 - T2 Exchange NMR experiment. Rather than varying the number of π pulses in the first CPMG cycle of the T2 - T2 Exchange NMR pulse sequence, as used to obtain the 2D correlation maps, it is fixed and small enough to act as a short T2-filter. By varying the storage time, a set of 1D measurements of T2 distributions can be obtained to reveal the effects of the migration dynamics combined with relaxation effects. This significantly reduces the required time to perform the experiment, allowing a more in-depth study of exchange dynamics and relaxation processes with improved signal-to-noise ratio. These aspects stand as basis of this novel experiment, T2-Filtered T2 - T2 Exchange NMR or simply T2 F-TREx.