American healthcare has been shrouded in a cloak of negativity for too long. Many doctors are more pessimistic about the state of healthcare than they were even a few decades ago. In spite of extraordinary advances in the clinical aspects of healthcare, the business side of medicine has created a downward spiral in physician spirit, resulting in unnecessary stress, zapped energy, a rise in interpersonal conflict and, ultimately and as a byproduct of this negativity, reduced patient satisfaction. This downward spiral needs to be--and can be--stemmed. This article discuss how insights from the field of positive psychology and social neuroscience can help healthcare providers and their organizations flourish, in both their professional practices and personal lives.