Medullary thyroid carcinoma as manifestation of the loss of heterozygosity in a patient with MEN1
Endocrinol Nutr. 2016 Aug-Sep;63(7):371-3.
doi: 10.1016/j.endonu.2016.03.005.
Epub 2016 May 27.
[Article in
English,
Spanish]
Affiliations
- 1 Department of Endocrinology and Nutrition, Hospital Clinic, Barcelona, Spain; Laboratory of Endocrine Disorders, IDIBAPS, Barcelona, Spain.
- 2 Department of Pathology, Hospital Clinic, Barcelona, Spain.
- 3 Department of Biochemistry and Molecular Genetics, CDB, Hospital Clínic, Barcelona, Spain.
- 4 Department of Endocrinology and Nutrition, Hospital Clinic, Barcelona, Spain; Laboratory of Endocrine Disorders, IDIBAPS, Barcelona, Spain; Faculty of Medicine, University of Barcelona, Spain. Electronic address: halperin@clinic.ub.es.
No abstract available
MeSH terms
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Adenoma / genetics
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Adult
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Biomarkers, Tumor / analysis
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Carcinoma, Medullary / genetics*
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Chromosomes, Human, Pair 11 / genetics*
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Female
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Humans
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Hyperparathyroidism, Primary / etiology
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Loss of Heterozygosity*
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Multiple Endocrine Neoplasia Type 1 / genetics*
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Mutation, Missense
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Parathyroid Neoplasms / genetics
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Pituitary Neoplasms / genetics
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Point Mutation
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Prolactinoma / genetics
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Proto-Oncogene Proteins / genetics*
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Thyroid Neoplasms / genetics*
Substances
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Biomarkers, Tumor
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MEN1 protein, human
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Proto-Oncogene Proteins