[Primary Synovial Sarcoma in the Anterior Mediastinum;Report of a Case]

Kyobu Geka. 2016 Jun;69(6):485-7.
[Article in Japanese]

Abstract

We report a rare case of synovial sarcoma in the anterior mediastinum. A 43-year-old man consulted our hospital with a complaint of dyspnea and chest discomfort. Chest computed tomography revealed an anterior mediastinal mass. Small open biopsy was performed, and the pathological examination revealed spindle-shaped cells with severe atypia. Tumor resection was performed. On pathology, fascicular and storiform patterns of spindle-shaped cells with severe atypia were noted. The tumor cells were positive for cytokeratin 7, vimentin, Bcl -2 and CD99, and the amplification of SYT-SSX fusion gene was also found. Therefore it was diagnosed as a synovial sarcoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biomarkers, Tumor / genetics
  • Biopsy
  • Humans
  • Male
  • Mediastinal Neoplasms / diagnostic imaging*
  • Mediastinal Neoplasms / genetics
  • Mediastinal Neoplasms / pathology*
  • Sarcoma, Synovial / diagnostic imaging*
  • Sarcoma, Synovial / genetics
  • Sarcoma, Synovial / pathology*
  • Sarcoma, Synovial / surgery
  • Tomography, X-Ray Computed

Substances

  • Biomarkers, Tumor