Comparative proteomic analysis of membrane microdomains isolated from two hyperlipidemic animal models

Biochim Biophys Acta. 2016 Sep;1864(9):1061-1071. doi: 10.1016/j.bbapap.2016.05.009. Epub 2016 May 26.

Authors

Viorel-Iulian Suica¹, Elena Uyy¹, Raluca Maria Boteanu¹, Luminita Ivan¹, Felicia Antohe²

Affiliations

¹ Institute of Cellular Biology and Pathology "N. Simionescu", 8, BP Hasdeu Street, PO Box: 35-14, 050568 Bucharest, Romania.
² Institute of Cellular Biology and Pathology "N. Simionescu", 8, BP Hasdeu Street, PO Box: 35-14, 050568 Bucharest, Romania. Electronic address: felicia.antohe@icbp.ro.

PMID: 27238564
DOI: 10.1016/j.bbapap.2016.05.009

No abstract available

Keywords: Atherosclerosis; Hyperlipidemia; Mass spectrometry; Membrane microdomains; Nano-chromatography; Proteomics.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antigen Presentation / drug effects
Apolipoproteins E / deficiency
Apolipoproteins E / genetics
Cell Movement / drug effects
Citric Acid Cycle / drug effects
Diet, High-Fat
Disease Models, Animal
Focal Adhesions / drug effects
Gene Ontology
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology*
Hyperlipidemias / drug therapy
Hyperlipidemias / etiology
Hyperlipidemias / genetics
Hyperlipidemias / metabolism*
Hypolipidemic Agents / pharmacology*
Leukocytes / cytology
Leukocytes / drug effects
Male
Membrane Microdomains / chemistry
Membrane Microdomains / drug effects*
Membrane Proteins / genetics
Membrane Proteins / isolation & purification*
Membrane Proteins / metabolism
Mesocricetus
Mice, Knockout
Molecular Sequence Annotation
Phagosomes / drug effects
Phagosomes / metabolism
Proteomics / methods*
Receptors, Cell Surface / genetics
Receptors, Cell Surface / metabolism
Signal Transduction
Tight Junctions / drug effects

Substances

Apolipoproteins E
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hypolipidemic Agents
Membrane Proteins
Receptors, Cell Surface
extracellular matrix receptor