Primary breast angiosarcoma in a young woman

Sara Iacoponi; Jackie Calleja; Gines Hernandez; Ricardo Sainz de la Cuesta

doi:10.1016/j.ijscr.2016.05.015

Primary breast angiosarcoma in a young woman

Int J Surg Case Rep. 2016:24:101-3. doi: 10.1016/j.ijscr.2016.05.015. Epub 2016 May 18.

Authors

Sara Iacoponi¹, Jackie Calleja², Gines Hernandez², Ricardo Sainz de la Cuesta²

Affiliations

¹ Gynecologic Oncology Unit. Quiron university hospital Madrid, Spain. Electronic address: saraiacoponi@hotmail.com.
² Gynecologic Oncology Unit. Quiron university hospital Madrid, Spain.

Abstract

Introduction: Angiosarcomas of the breast are a rare subtype of sarcomas that frequently are diagnosed after radiation therapy for primary breast cancer. Primary angiosarcomas are rare entities accounting 0.05% of all malignant breast neoplasm.

Presentation of case: We report a case of primary angiosarcoma of the breast in a 25 years woman, with no previous radiotherapy, treated with a total mastectomy followed by radio-chemotherapy.

Discussion: Total mastectomy appears to be the only treatment known that has proven to benefit these patients. Adjuvant treatment has not proven value up until today. The 5-year disease free survival for grade 1 tumors can be as high as 76%, and up to 15% for grade 3.

Conclusion: Due to the rarity of these tumors there is no standard therapies approach.

Keywords: Breast cancer; Diffusion-weighted magnetic resonance imaging (MR-DWI); Mastectomy; Primary angiosarcoma; Radiotherapy; Young woman.