Toxicology of freshwater cyanobacteria

J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2016 Jul 2;34(3):137-168. doi: 10.1080/10590501.2016.1193923.

Abstract

Many chemical contaminants in drinking water have been shown to cause adverse health effects in humans after prolonged exposure. Cyanobacteria are one of the most potent and diverse groups of photosynthetic prokaryotes. One key component of cyanobacterial success in the environment is the production of potent toxins as secondary metabolites, which have been responsible for numerous adverse health impacts in humans. Anthropogenic activities have led to the increase of eutrophication in freshwater bodies' worldwide, causing cyanobacterial blooms to become more frequent. The present article will discuss about harmful cyanobacteria and their toxicology with special references to microcystin, nodularin, and cylindrospermopsin.

Keywords: Cyanobacteria; cyanotoxins; cylindrospermopsin; harmful algal blooms; microcystin.

Publication types

  • Review

MeSH terms

  • Alkaloids
  • Bacterial Toxins / metabolism
  • Bacterial Toxins / toxicity*
  • Cyanobacteria / physiology*
  • Cyanobacteria Toxins
  • Eutrophication
  • Fresh Water / chemistry
  • Fresh Water / microbiology*
  • Microcystins / toxicity
  • Peptides, Cyclic / toxicity
  • Uracil / analogs & derivatives
  • Uracil / toxicity
  • Water Microbiology*

Substances

  • Alkaloids
  • Bacterial Toxins
  • Cyanobacteria Toxins
  • Microcystins
  • Peptides, Cyclic
  • nodularin
  • cylindrospermopsin
  • Uracil