Abstract
Knowledge about immunity to Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels is essential for infection control and vaccination. A longitudinal study of 11 dam-calf pairs showed that calves lose maternal MERS-CoV antibodies 5-6 months postparturition and are left susceptible to infection, indicating a short window of opportunity for vaccination.
Keywords:
MERS-CoV; Middle East respiratory syndrome coronavirus; calves; camel; dams; dromedary; immunity; infection; maternal antibodies; risk assessment; viruses.
MeSH terms
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Animal Diseases / immunology*
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Animal Diseases / transmission
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Animal Diseases / virology*
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Animals
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Antibodies, Viral / immunology
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Camelus / virology*
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Cattle
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Cattle Diseases / immunology
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Cattle Diseases / transmission
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Cattle Diseases / virology
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Coronavirus Infections / veterinary*
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Immunoglobulin G / blood
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Immunoglobulin G / immunology
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Longitudinal Studies
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Middle East Respiratory Syndrome Coronavirus / classification
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Middle East Respiratory Syndrome Coronavirus / genetics
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Middle East Respiratory Syndrome Coronavirus / immunology*
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Middle East Respiratory Syndrome Coronavirus / isolation & purification
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RNA, Viral
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Zoonoses
Substances
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Antibodies, Viral
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Immunoglobulin G
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RNA, Viral