An acute gastroenteritis outbreak caused by GII.17 norovirus in Jiangsu Province, China

Int J Infect Dis. 2016 Aug:49:30-2. doi: 10.1016/j.ijid.2016.05.004. Epub 2016 May 17.

Abstract

Noroviruses are a common cause of acute gastroenteritis around the world; however, reports of outbreaks caused by GII.17 norovirus are rare. An outbreak caused by GII.17 norovirus in a senior high school in Wuxi, Jiangsu Province, China is reported here. An epidemiological investigation, pathogen detection, and case-control study were performed. Epidemiological data combined with the epidemic curve indicated that this outbreak was a point source type initially, followed by secondary transmission. The first case was identified as most likely the source of the outbreak. Risk analysis showed exposure to patients and sharing a communal water cooler to be associated with the spread of infection. Sequence analysis of GII-positive samples confirmed that the norovirus GII.17 variant was the etiological agent of this outbreak.

Keywords: Disease outbreak; Molecular epidemiology; Noroviruses.

MeSH terms

  • Caliciviridae Infections / epidemiology
  • Caliciviridae Infections / virology*
  • Case-Control Studies
  • China / epidemiology
  • Disease Outbreaks
  • Epidemics
  • Gastroenteritis / epidemiology
  • Gastroenteritis / virology*
  • Genotype
  • Humans
  • Norovirus / classification
  • Norovirus / genetics
  • Norovirus / isolation & purification*
  • Norovirus / physiology
  • Phylogeny