Comparison of severe acute respiratory illness (sari) and clinical pneumonia case definitions for the detection of influenza virus infections among hospitalized patients, western Kenya, 2009-2013

Influenza Other Respir Viruses. 2016 Jul;10(4):333-9. doi: 10.1111/irv.12382. Epub 2016 Mar 23.

Abstract

Although the severe acute respiratory illness (SARI) case definition is increasingly used for inpatient influenza surveillance, pneumonia is a more familiar term to clinicians and policymakers. We evaluated WHO case definitions for severe acute respiratory illness (SARI) and pneumonia (Integrated Management of Childhood Illnesses (IMCI) for children aged <5 years and Integrated Management of Adolescent and Adult Illnesses (IMAI) for patients aged ≥13 years) for detecting laboratory-confirmed influenza among hospitalized ARI patients. Sensitivities were 84% for SARI and 69% for IMCI pneumonia in children aged <5 years and 60% for SARI and 57% for IMAI pneumonia in patients aged ≥13 years. Clinical pneumonia case definitions may be a useful complement to SARI for inpatient influenza surveillance.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Female
  • Hospitalization
  • Humans
  • Infant
  • Influenza, Human / epidemiology
  • Influenza, Human / therapy
  • Influenza, Human / virology*
  • Kenya / epidemiology
  • Male
  • Middle Aged
  • Orthomyxoviridae / genetics
  • Orthomyxoviridae / isolation & purification
  • Orthomyxoviridae / physiology*
  • Pneumonia / epidemiology
  • Pneumonia / therapy
  • Pneumonia / virology*
  • Respiratory Tract Infections / epidemiology
  • Respiratory Tract Infections / therapy
  • Respiratory Tract Infections / virology*
  • Sentinel Surveillance
  • Young Adult