Antifungal Susceptibility Testing of Ascomycetous Yeasts Isolated from Animals

Sergio Álvarez-Pérez; Marta E García; Teresa Peláez; Eva Martínez-Nevado; José L Blanco

doi:10.1128/AAC.00306-16

Antifungal Susceptibility Testing of Ascomycetous Yeasts Isolated from Animals

Antimicrob Agents Chemother. 2016 Jul 22;60(8):5026-8. doi: 10.1128/AAC.00306-16. Print 2016 Aug.

Authors

Sergio Álvarez-Pérez¹, Marta E García¹, Teresa Peláez², Eva Martínez-Nevado³, José L Blanco⁴

Affiliations

¹ Department of Animal Health, Faculty of Veterinary, Universidad Complutense de Madrid, Madrid, Spain.
² Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain Department of Medicine, Faculty of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
³ Zoo-Aquarium Madrid, Madrid, Spain.
⁴ Department of Animal Health, Faculty of Veterinary, Universidad Complutense de Madrid, Madrid, Spain jlblanco@ucm.es.

Abstract

Recent studies suggest that antifungal resistance in yeast isolates of veterinary origin may be an underdiagnosed threat. We tested a collection of 92 ascomycetous yeast isolates that were obtained in Spain from birds, mammals and insects for antifungal susceptibility. MICs to amphotericin B and azoles were low, and no resistant isolates were detected. Despite these results, and given the potential role of animals as reservoirs of resistant strains, continuous monitoring of antifungal susceptibility in the veterinary setting is recommended.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amphotericin B / pharmacology
Animals
Antifungal Agents / pharmacology*
Azoles / pharmacology
Birds / microbiology
Drug Resistance, Fungal
Insecta / microbiology
Mammals / microbiology
Microbial Sensitivity Tests
Yeasts / drug effects*

Substances

Antifungal Agents
Azoles
Amphotericin B

Grants and funding

This work was funded by Universidad Complutense de Madrid-Banco Santander (grant 920630) through the Research Groups Funding Program (to J.L.B.) and by “Juan de la Cierva” postdoctoral contract JCI-2012-12396 (to S.A.-P.). The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.