txCoords: A Novel Web Application for Transcriptomic Peak Re-Mapping

IEEE/ACM Trans Comput Biol Bioinform. 2017 May-Jun;14(3):746-748. doi: 10.1109/TCBB.2016.2568178. Epub 2016 May 16.

Abstract

Since the development of new technologies such as RIP-Seq and m6A-seq, peak calling has become an important step in transcriptomic sequencing data analysis. However, many of the reported genomic coordinates of transcriptomic peaks are incorrect owing to negligence of the introns. There is currently a lack of a convenient tool to address this problem. Here, we present txCoords, a novel and easy-to-use web application for transcriptomic peak re-mapping. txCoords can be used to correct the incorrectly reported transcriptomic peaks and retrieve the true sequences. It also supports visualization of the re-mapped peaks in a schematic figure or from the UCSC Genome Browser. Our web server is freely available at http://www.bioinfo.tsinghua.edu.cn/txCoords.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain / metabolism
  • Brain Chemistry / genetics
  • Gene Expression Profiling / methods*
  • Genomics / methods*
  • Humans
  • Internet*
  • Models, Biological
  • Software*
  • Transcriptome / genetics*