Activation of wnt/β-catenin signaling blocks monocyte-macrophage differentiation through antagonizing PU.1-targeted gene transcription

Leukemia. 2016 Oct;30(10):2106-2109. doi: 10.1038/leu.2016.146. Epub 2016 May 23.

Authors

Y Sheng¹, W Ju^{2

1}, Y Huang³, J Li², H Ozer¹, X Qiao⁴, Z Qian¹

Affiliations

¹ Department of Medicine and Cancer Center, University of Illinois at Chicago, Chicago, IL, USA.
² College of Public Health, Jilin University, Jilin, China.
³ Section of Gastroenterology, Department of Medicine, The University of Chicago, Chicago, IL, USA.
⁴ Department of Pediatrics, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Differentiation*
Humans
Macrophages / cytology*
Mice
Monocytes / cytology*
Proto-Oncogene Proteins / physiology*
Signal Transduction*
Trans-Activators / physiology*
Transcription, Genetic / physiology*
Wnt Proteins / metabolism*
beta Catenin / metabolism*

Substances

Proto-Oncogene Proteins
Trans-Activators
Wnt Proteins
beta Catenin
proto-oncogene protein Spi-1

Grants and funding