The growing story of (ARABIDOPSIS) CRINKLY 4

Nathan Czyzewicz; Natalia Nikonorova; Matthew R Meyer; Priyanka Sandal; Shweta Shah; Lam Dai Vu; Kris Gevaert; A Gururaj Rao; Ive De Smet

doi:10.1093/jxb/erw192

The growing story of (ARABIDOPSIS) CRINKLY 4

J Exp Bot. 2016 Aug;67(16):4835-47. doi: 10.1093/jxb/erw192. Epub 2016 May 21.

Authors

Nathan Czyzewicz¹, Natalia Nikonorova², Matthew R Meyer³, Priyanka Sandal³, Shweta Shah³, Lam Dai Vu⁴, Kris Gevaert⁵, A Gururaj Rao³, Ive De Smet⁶

Affiliations

¹ Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough, LE12 5RD, UK.
² Department of Plant Systems Biology, VIB, B-9052 Ghent University, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium.
³ Roy J. Carver Department of Biochemistry Biophysics and Molecular Biology, Iowa State University, Ames, IA, 50011, USA.
⁴ Department of Plant Systems Biology, VIB, B-9052 Ghent University, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium Medical Biotechnology Center, VIB, 9000 Ghent, Belgium Department of Biochemistry, Ghent University, 9000 Ghent, Belgium.
⁵ Medical Biotechnology Center, VIB, 9000 Ghent, Belgium Department of Biochemistry, Ghent University, 9000 Ghent, Belgium.
⁶ Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough, LE12 5RD, UK Department of Plant Systems Biology, VIB, B-9052 Ghent University, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium Centre for Plant Integrative Biology, University of Nottingham, Loughborough, LE12 5RD, UK ive.desmet@psb.vib-ugent.be.

PMID: 27208540
DOI: 10.1093/jxb/erw192

Abstract

Receptor kinases play important roles in plant growth and development, but only few of them have been functionally characterized in depth. Over the past decade CRINKLY 4 (CR4)-related research has peaked as a result of a newly discovered role of ARABIDOPSIS CR4 (ACR4) in the root. Here, we comprehensively review the available (A)CR4 literature and describe its role in embryo, seed, shoot, and root development, but we also flag an unexpected role in plant defence. In addition, we discuss ACR4 domains and protein structure, describe known ACR4-interacting proteins and substrates, and elaborate on the transcriptional regulation of ACR4 Finally, we address the missing knowledge in our understanding of ACR4 signalling.

Keywords: ACR4; Arabidopsis; embryo; epidermis; flower; maize; receptor kinase; rice; root; seed..

Publication types

Review

MeSH terms

Arabidopsis / genetics*
Arabidopsis / growth & development
Arabidopsis / immunology
Arabidopsis / metabolism
Arabidopsis Proteins / genetics*
Arabidopsis Proteins / metabolism
Plant Immunity
Plant Roots / genetics
Plant Roots / growth & development
Plant Roots / metabolism
Plant Shoots / genetics
Plant Shoots / growth & development
Plant Shoots / metabolism
Protein Serine-Threonine Kinases / genetics*
Protein Serine-Threonine Kinases / metabolism
Receptors, Cell Surface / genetics*
Receptors, Cell Surface / metabolism
Seeds / genetics
Seeds / growth & development
Seeds / metabolism

Substances

Arabidopsis Proteins
Receptors, Cell Surface
ACR4 protein, Arabidopsis
Protein Serine-Threonine Kinases

Grants and funding

BB/H022457/1/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom