Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects

Affiliations

• ¹ Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.
• ² Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
• ³ Department of Pathobiology, Faculty of Veterinary Medicine, Dutch Molecular Pathology Center, Utrecht University, 3584 CL, Utrecht, The Netherlands.
• ⁴ Division of Molecular Genetics, Department of Pediatrics, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
• ⁵ Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands. r.j.pasterkamp@umcutrecht.nl.