Population-Level Effect of Cholera Vaccine on Displaced Populations, South Sudan, 2014

Emerg Infect Dis. 2016 Jun;22(6):1067-70. doi: 10.3201/eid2206.151592.

Abstract

Following mass population displacements in South Sudan, preventive cholera vaccination campaigns were conducted in displaced persons camps before a 2014 cholera outbreak. We compare cholera transmission in vaccinated and unvaccinated areas and show vaccination likely halted transmission within vaccinated areas, illustrating the potential for oral cholera vaccine to stop cholera transmission in vulnerable populations.

Keywords: South Sudan; Vibrio cholerae; bacteria; cholera; diarrhea; displaced persons; transmission dynamics; vaccine; vulnerable populations.

MeSH terms

  • Administration, Oral
  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Cholera / epidemiology*
  • Cholera / prevention & control*
  • Cholera Vaccines / administration & dosage
  • Cholera Vaccines / immunology*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care
  • Population Surveillance
  • South Sudan / epidemiology
  • Vaccination
  • Vibrio cholerae / immunology*
  • Young Adult

Substances

  • Cholera Vaccines