Fine-Needle Diathermy with Simultaneous Subconjunctival Bevacizumab

Semin Ophthalmol. 2017;32(5):550-552. doi: 10.3109/08820538.2015.1123738. Epub 2016 May 18.

Abstract

Purpose: To describe our experience of the use of subconjunctival bevacizumab in conjunction with fine-needle diathermy for the treatment of corneal vascularization.

Methods: Retrospective analysis of cases treated between 2010 and 2013.

Results: Those patients with corneal lipid deposition had good results following treatment with 3/5 cases requiring more than one session of treatment. A single patient with severe atopy and multiple previous failed penetrating keratoplasty underwent five sessions of treatment but his third graft subsequently also failed.

Conclusion: Concurrent use of subconjunctival bevacizumab with FND gives good results in patients with lipid deposition; however, the management of cases with ongoing inflammatory processes is much more challenging.

Keywords: Cornel neovascularization; fine-needle diathermy.

MeSH terms

  • Angiogenesis Inhibitors / administration & dosage*
  • Bevacizumab / administration & dosage*
  • Corneal Neovascularization / therapy*
  • Diathermy / methods*
  • Female
  • Humans
  • Injections, Intraocular
  • Male
  • Middle Aged
  • Retrospective Studies
  • Visual Acuity

Substances

  • Angiogenesis Inhibitors
  • Bevacizumab