Delayed healing of oral mucosa in a diabetic rat model: Implication of TNF-α, IL-1β and FGF-2

Life Sci. 2016 Jun 15:155:36-47. doi: 10.1016/j.lfs.2016.04.033. Epub 2016 May 14.

Authors

Luiz André C Brizeno¹, Ana Maria S Assreuy¹, Ana Paula N N Alves², Fabrício B Sousa², Paulo Goberlânio de B Silva³, Suzana Cantanhede O Machado de Sousa⁴, Nelise A S Lascane⁴, Janaína Serra-Azul M Evangelista¹, Mário Rogério L Mota²

Affiliations

¹ Superior Institute of Biomedical Sciences (ISCB), State University of Ceará (UECE), Ceará, Brazil.
² Laboratory of Oral Pathology, Pharmacy, Dentistry and Nursing College, Federal University of Ceara (UFC), Brazil.
³ Laboratory of Oral Pathology, Pharmacy, Dentistry and Nursing College, Federal University of Ceara (UFC), Brazil. Electronic address: paulo_goberlanio@yahoo.com.br.
⁴ Stomatology Department, Dentistry Faculty, São Paulo University (USP), Brazil.

PMID: 27188585
DOI: 10.1016/j.lfs.2016.04.033

No abstract available

Keywords: Diabetes; Mucosa; Oral ulcer; Rat; Wound healing.

MeSH terms

Animals
Diabetes Mellitus, Experimental / metabolism
Diabetes Mellitus, Experimental / pathology
Diabetes Mellitus, Experimental / physiopathology*
Disease Models, Animal*
Fibroblast Growth Factor 2 / physiology*
Interleukin-1beta / physiology*
Male
Mouth Diseases / metabolism
Mouth Diseases / pathology
Mouth Diseases / physiopathology*
Rats
Rats, Wistar
Tumor Necrosis Factor-alpha / physiology*
Wound Healing*

Substances

Interleukin-1beta
Tumor Necrosis Factor-alpha
Fibroblast Growth Factor 2