Cryptococcal Meningitis Presenting as a Complication in HIV-infected Children: A Case Series From Sub-Saharan Africa

Pediatr Infect Dis J. 2016 Sep;35(9):979-80. doi: 10.1097/INF.0000000000001212.

Abstract

Cryptococcal meningitis is a leading infectious disease worldwide as a result of the high burden of HIV and AIDS, although its cumulative incidence is very low in children compared with that in adults. Very few studies involving the disease in children have been reported including sub-Saharan Africa, with the highest prevalence of HIV-infected children in the world. We summarize 5 cases of children diagnosed with cryptococcal meningitis at a tertiary hospital in Harare, Zimbabwe, between October 1, 2013, and September 30, 2014.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • AIDS-Related Opportunistic Infections* / diagnosis
  • AIDS-Related Opportunistic Infections* / drug therapy
  • AIDS-Related Opportunistic Infections* / epidemiology
  • Adolescent
  • Africa South of the Sahara
  • Anti-Retroviral Agents / therapeutic use
  • Child
  • HIV Infections / complications*
  • Humans
  • Male
  • Meningitis, Cryptococcal* / diagnosis
  • Meningitis, Cryptococcal* / drug therapy
  • Meningitis, Cryptococcal* / epidemiology
  • Retrospective Studies

Substances

  • Anti-Retroviral Agents