Combination of soya protein and polydextrose reduces energy intake and glycaemic response via modulation of gastric emptying rate, ghrelin and glucagon-like peptide-1 in Chinese

Br J Nutr. 2016 Jun;115(12):2130-7. doi: 10.1017/S0007114516001689.

Abstract

The short-term effect of soya protein, polydextrose and their combination on energy intake (EI) was investigated in Chinese. In total, twenty-seven healthy, normotensive and lean Chinese men aged 21-40 years were given four different soyabean curd preloads with or without polydextrose. The study was a repeated-measure, randomised, cross-over design. The consumption of high-protein soyabean curd alone or in addition with polydextrose as a preload led to greater reduction in EI at a subsequent meal. A similar observation was also found after intake of low-protein soyabean curd with polydextrose. The gut hormone responses mirrored the reduction in food intake. It appears that incorporation of polydextrose either with low- or high-protein soyabean curd could be a potential strategy to reduce EI and assist with weight management. The popular consumption of soyabean curd in Chinese makes it an ideal vehicle for incorporation of polydextrose. This evidence-based dietary approach can serve as a guideline for developing functional foods for weight reduction and weight maintenance.

Keywords: EI energy intake; Food intake; GER gastric emptying rate; GLP-1 plasma glucagon-like peptide-1; GR glycaemic response; Gastric emptying; Gut hormones; HP high protein; HPP high protein with polydextrose; IAUC incremental AUC; LP low protein; LPP low protein with polydextrose; Polydextrose; Soyabean curd; VAS visual analogue scales.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Appetite / drug effects
  • Blood Glucose / metabolism*
  • China
  • Cross-Over Studies
  • Dietary Carbohydrates / pharmacology
  • Dietary Proteins / pharmacology
  • Eating / drug effects*
  • Energy Intake / drug effects*
  • Functional Food
  • Gastric Emptying / drug effects*
  • Gastrointestinal Hormones / metabolism*
  • Ghrelin / metabolism
  • Glucagon-Like Peptide 1 / metabolism
  • Glucans / pharmacology*
  • Glycemic Index
  • Humans
  • Male
  • Meals
  • Obesity / diet therapy
  • Obesity / metabolism
  • Soybean Proteins / pharmacology*
  • Weight Loss
  • Young Adult

Substances

  • Blood Glucose
  • Dietary Carbohydrates
  • Dietary Proteins
  • Gastrointestinal Hormones
  • Ghrelin
  • Glucans
  • Soybean Proteins
  • Glucagon-Like Peptide 1
  • polydextrose