Primary signet-ring cell adenocarcinoma of the head and neck: a case study and brief review

Abstract

We present a patient who had an aggressive primary signet-ring cell adenocarcinoma in the oral cavity that spread rapidly and led to his death. Most reports describe an indolent clinical course, but further reports are needed to better evaluate the particular clinical characteristics and course of this uncommon and biologically variable condition.

Keywords: Head and neck; Metastasis; Oral cavity; Outcome; Primary signet-ring cell adenocarcinoma; Review; Signet ring lesion.