ISCHEMIA in chronic kidney disease: improving the representation of patients with chronic kidney disease in cardiovascular trials

Christina M Wyatt; Matthew Shineski; Glenn M Chertow; Sripal Bangalore

doi:10.1016/j.kint.2016.03.012

ISCHEMIA in chronic kidney disease: improving the representation of patients with chronic kidney disease in cardiovascular trials

Kidney Int. 2016 Jun;89(6):1178-9. doi: 10.1016/j.kint.2016.03.012.

Authors

Christina M Wyatt¹, Matthew Shineski², Glenn M Chertow³, Sripal Bangalore⁴

Affiliations

¹ Department of Medicine, Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address: christina.wyatt@mssm.edu.
² ISCHEMIA Clinical Coordinating Center, New York University School of Medicine, New York, New York, USA.
³ Department of Medicine, Division of Nephrology, Stanford School of Medicine, Stanford, California, USA.
⁴ Department of Medicine, Division of Cardiology, New York University School of Medicine, New York, New York, USA.

PMID: 27181770
DOI: 10.1016/j.kint.2016.03.012

Abstract

Despite the high cardiovascular risk associated with chronic kidney disease, a recent systematic review confirmed that patients with kidney disease remain underrepresented in cardiovascular trials. Two ongoing trials are assessing the risk:benefit of aggressive evaluation and intervention for ischemic heart disease in patients with advanced chronic kidney disease.

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MeSH terms

Cardiovascular Diseases*
Chronic Disease
Humans
Myocardial Ischemia
Renal Insufficiency, Chronic*
Risk Assessment
Risk Factors