Monitoring 3D dose distributions in proton therapy by reconstruction using an iterative method

Young-Hak Kim; Changyeon Yoon; Wonho Lee

doi:10.1016/j.apradiso.2016.05.005

Monitoring 3D dose distributions in proton therapy by reconstruction using an iterative method

Appl Radiat Isot. 2016 Aug:114:33-9. doi: 10.1016/j.apradiso.2016.05.005. Epub 2016 May 7.

Authors

Young-Hak Kim¹, Changyeon Yoon¹, Wonho Lee²

Affiliations

¹ Department of Bio-Convergence Engineering, Korea University, Hana Science Hall 277, Korea Univ. Anam Campus, Anam-dong 5-ga, Seongbuk-gu, Seoul, Korea.
² School of Health and Environmental Science, Korea University, Hana Science Hall 278, Korea Univ. Anam Campus, Anam-dong 5-ga, Seongbuk-gu, Seoul, Korea. Electronic address: wonhol@korea.ac.kr.

PMID: 27179145
DOI: 10.1016/j.apradiso.2016.05.005

Abstract

The Bragg peak of protons can be determined by measuring prompt γ-rays. In this study, prompt γ-rays detected by single-photon emission computed tomography with a geometrically optimized collimation system were reconstructed by an iterative method. The falloff position by iterative method (52.48mm) was most similar to the Bragg peak (52mm) of an 80MeV proton compared with those of back-projection (54.11mm) and filtered back-projection (54.91mm) methods. Iterative method also showed better image performance than other methods.

Keywords: Bragg peak; Iterative reconstruction method; Prompt γ-Rays; Proton therapy; Single-Photon Emission Computed Tomography (SPECT).

MeSH terms

Computer Simulation
Gamma Rays
Humans
Image Processing, Computer-Assisted
Imaging, Three-Dimensional
Neoplasms / radiotherapy
Phantoms, Imaging
Proton Therapy*
Protons
Radiation Monitoring / statistics & numerical data
Radiotherapy Dosage*
Radiotherapy, Conformal
Spectrometry, Gamma / statistics & numerical data
Tomography, Emission-Computed, Single-Photon

Substances

Protons