Gums' based delivery systems: Review on cashew gum and its derivatives

Carbohydr Polym. 2016 Aug 20:147:188-200. doi: 10.1016/j.carbpol.2016.02.042. Epub 2016 Feb 18.

Abstract

The development of delivery systems using natural polymers such as gums offers distinct advantages, such as, biocompatibility, biodegradability, and cost effectiveness. Cashew gum (CG) has rheological and mucoadhesive properties that can find many applications, among which the design of delivery systems for drugs and other actives such as larvicide compounds. In this review CG is characterized from its source through to the process of purification and chemical modification highlighting its physicochemical properties and discussing its potential either for micro and nanoparticulate delivery systems. Chemical modifications of CG increase its reactivity towards the design of delivery systems, which provide a sustained release effect for larvicide compounds. The purification and, the consequent characterization of CG either original or modified are of utmost importance and is still a continuing challenge when selecting the suitable CG derivative for the delivery of larvicide compounds.

Keywords: Cashew gum; Chemical derivatives; Delivery system; Physicochemical properties; Purification; Submicron particle.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anacardium / chemistry*
  • Drug Carriers / chemistry
  • Plant Gums / chemistry*
  • Plant Gums / isolation & purification

Substances

  • Drug Carriers
  • Plant Gums