Methotrexate analogues. 10. Direct coupling of methotrexate and diethyl L-glutamate in the presence of peptide bond-forming reagents

J Med Chem. 1978 Feb;21(2):170-5. doi: 10.1021/jm00200a005.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cells, Cultured
  • Glutamates*
  • Humans
  • Indicators and Reagents
  • Leukemia L1210 / drug therapy
  • Leukemia, Lymphoid / metabolism
  • Methotrexate / analogs & derivatives*
  • Methotrexate / chemical synthesis
  • Methotrexate / therapeutic use
  • Mice
  • Stereoisomerism

Substances

  • Glutamates
  • Indicators and Reagents
  • Methotrexate