TGFβ1 derived from endothelial cells inhibits melanogenesis

Pigment Cell Melanoma Res. 2016 Jul;29(4):477-80. doi: 10.1111/pcmr.12491.

Authors

Ji-Youn Park¹, Misun Kim^{1

2

3}, Tae Jun Park^{2

3

4}, Hee Young Kang^{1

2

3}

Affiliations

¹ Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.
² Chronic Inflammatory Disease Research Center, Ajou University School of Medicine, Suwon, Korea.
³ Department of Biomedical Science, The Graduate School, Ajou University, Suwon, Korea.
⁴ Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, Korea.

PMID: 27172887
DOI: 10.1111/pcmr.12491

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cells, Cultured
Culture Media, Conditioned / pharmacology
Dermis / blood supply*
Down-Regulation
Endothelial Cells / metabolism*
Gene Expression Regulation / drug effects
Humans
Melanins / biosynthesis
Melanins / genetics
Melanocytes / drug effects*
Melanocytes / metabolism
Melanoma, Experimental
Mice
Microphthalmia-Associated Transcription Factor / biosynthesis
Microphthalmia-Associated Transcription Factor / genetics
Microvessels / cytology
Monophenol Monooxygenase / biosynthesis
Monophenol Monooxygenase / genetics
Paracrine Communication
Recombinant Proteins / pharmacology
Transforming Growth Factor beta1 / metabolism
Transforming Growth Factor beta1 / pharmacology
Transforming Growth Factor beta1 / physiology*

Substances

Culture Media, Conditioned
MITF protein, human
Melanins
Microphthalmia-Associated Transcription Factor
Mitf protein, mouse
Recombinant Proteins
TGFB1 protein, human
Transforming Growth Factor beta1
Monophenol Monooxygenase